Taurohyodeoxycholic acid sodium salt Inhibitor

Name: Taurohyodeoxycholic acid sodium salt Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759675
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759675

Taurohyodeoxycholic acid sodium salt, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Taurohyodeoxycholic acid sodium salt, Inhibitor

Full Product Name

Taurohyodeoxycholic acid sodium salt

Product Synonym Names

Taurodeoxychloic Acid sodium hydrate; Sodium taurodeoxycholate monohydrate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

540.71

Solubility

DMSO: 125mg/mL (231.18mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C26H47NNaO7S+

SMILES

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]

CAS Number

110026-03-4

Target & IC50

Caspase

In Vitro

At all infusion rates, taurohyodeoxycholic acid caused a greater (P <0.001) secretion of biliary lecithin compared to the other bile salts. There were no significant differences in the biliary secretion of cholesterol and proteins. Electron microscopy showed the recruitment of vesicles and lamellar bodies around and within bile canaliculi. In conclusion, taurohyodeoxycholic promotes a biliary lecithin secretion greater than expected from physicochemical predictions, representing a novel secretory property with potential pharmacological relevance[1].

Product Categories/Family for Taurohyodeoxycholic acid sodium salt, inhibitor

Apoptosis; Caspase; Proteases/Proteasome

Product References and Citations for Taurohyodeoxycholic acid sodium salt, inhibitor

Angelico M, Baiocchi L, Nistri A, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat[J]. Digestive Diseases & Sciences, 1994, 39(11):2389-2397.
Angelico M, Baiocchi L, Nistri A, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat[J]. Digestive Diseases & Sciences, 1994, 39(11):2389-2397.
Roda A, Piazza F, Baraldini M, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat[J]. Hepatology, 1998, 27.
Roda A, Piazza F, Baraldini M, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat[J]. Hepatology, 1998, 27.

Other Notes

Small volumes of Taurohyodeoxycholic acid sodium salt, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Taurohyodeoxycholic acid sodium salt purchase

MBS5759675 is an inhibitor targeting Taurohyodeoxycholic acid sodium salt.