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N-p-trans-Coumaroyltyramine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759780

MBS5759780 is an inhibitor targeting N-p-trans-Coumaroyltyramine. N-p-trans-Coumaroyltyramine is an inhibitor on acetylcholinesterase (AChE). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
N-p-trans-Coumaroyltyramine, Inhibitor
Full Product Name
N-p-trans-Coumaroyltyramine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
283.33
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H17NO3
SMILES
Oc1ccc(CCNC(/C=C/c(cc2)ccc2O)=O)cc1
CAS Number
36417-86-4
Target & IC50
AChR
In Vitro
The methanolic extract of the twigs of Celtis chinensis was found to show inhibitory activity on acetylcholinesterase (AChE), an enzyme that plays a role in the metabolic hydrolysis of AChours. Bioassay-guided fractionation of the methanolic extract resulted in the isolation of N-p-trans-Coumaroyltyramine, as an inhibitor on AChE[1]

Product Categories/Family for N-p-trans-Coumaroyltyramine, inhibitor

Neuroscience; AChR

Product References and Citations for N-p-trans-Coumaroyltyramine, inhibitor

Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch. Pharm. Res.,2003, 26(9):735-8.
Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch. Pharm. Res.,2003, 26(9):735-8.
Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity.Nat Prod Commun. 2012 Jun;7(6):753-5.
Chemical constituents from roots of Datura metel.Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(8):1654-1661.

Other Notes

Small volumes of N-p-trans-Coumaroyltyramine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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