Irisolidone Inhibitor

Name: Irisolidone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759785
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759785

Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13uM. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Irisolidone, Inhibitor

Full Product Name

Irisolidone

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

314.29

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C17H14O6

SMILES

COc(cc1)ccc1C(C(c1c2O)=O)=COc1cc(O)c2OC

CAS Number

2345-17-7

Target & IC50

IL Receptor
NF-kappaB
TNF-alpha

Product Categories/Family for Irisolidone, inhibitor

Immunology/Inflammation; IL Receptor; NF-kappab; Apoptosis

Product References and Citations for Irisolidone, inhibitor

Natural and synthetic flavonoids, novel blockers of the volume-regulated anion channels, inhibit endothelial cell proliferation.Pflugers Arch. 2018 Jun 30.
Natural and synthetic flavonoids, novel blockers of the volume-regulated anion channels, inhibit endothelial cell proliferation.Pflugers Arch. 2018 Jun 30.
Inhibitory activity of isoflavones of Pueraria flowers on nitric oxide production from lipopolysaccharide-activated primary rat microglia.J Asian Nat Prod Res. 2009 Jun;11(6):471-81.
Protection against neurodegenerative diseases of Iris pseudopumila extracts and their constituents.Fitoterapia. 2009 Jan;80(1):62-7.
Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica. Arch Pharm Res. 2008 Jul;31(7):886-90.

Other Notes

Small volumes of Irisolidone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Irisolidone purchase

MBS5759785 is an inhibitor targeting Irisolidone.