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Swertiaperennin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759795

MBS5759795 is an inhibitor targeting Swertiaperennin. Swertiaperennin is a natural product More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Swertiaperennin, Inhibitor
Full Product Name
Swertiaperennin
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
288.25
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H12O6
SMILES
COc(cc1O)cc(Oc(c2c3O)ccc3OC)c1C2=O
CAS Number
22172-17-4
Target & IC50
Others
In Vitro
Three known xanthones were isolated from the crude methanolic extract of the roots: gentiacaulein, gentiakochianin, and Swertiaperennin. The first two showed a vasorelaxing activity in rat aortic preparations, pre-contracted by 3microM norepinephrine (pIC50 = 5.00 +/- 0.032 for gentiacaulein, pIC50 = 4.95 +/- 0.068 for gentiakochianin), 20mM KCl (pIC50 = 4.90 +/- 0.15 for gentiacaulein; 4.59 +/- 0.069 for gentiakochianin), or 5mM caffeine; on the contrary, in the same conditions, Swertiaperennin did not show any vasodilator effect.

Product References and Citations for Swertiaperennin, inhibitor

The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana.Planta Med. 2003 Aug;69(8):770-2.

Other Notes

Small volumes of Swertiaperennin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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