Deoxypodophyllotoxin Inhibitor

Name: Deoxypodophyllotoxin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759837
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759837

Deoxypodophyllotoxin shows cytotoxic, antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Deoxypodophyllotoxin, Inhibitor

Full Product Name

Deoxypodophyllotoxin

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

398.41

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C22H22O7

SMILES

[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1C2

CAS Number

19186-35-7

Target & IC50

Bcl-2
Caspase
PARP
microtubule
Autophagy
Apoptosis

Product Categories/Family for Deoxypodophyllotoxin, inhibitor

Apoptosis; BCL; Cytoskeletal Signaling; Autophagy

Product References and Citations for Deoxypodophyllotoxin, inhibitor

Kim SH, et al. Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells. Pharmacol Rep. 2017 Oct;69(5):878-884.
Kim SH, et al. Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells. Pharmacol Rep. 2017 Oct;69(5):878-884.
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects. Int J Biochem Cell Biol. 2013 Aug;45(8):1710-9.
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects. Int J Biochem Cell Biol. 2013 Aug;45(8):1710-9.
Pharmacological effect of deoxypodophyllotoxin: a medicinal agent of plant origin, on mammalian neurons.Neurotoxicology. 2010 Dec;31(6):680-6.
Insecticidal activity of deoxypodophyllotoxin, isolated from Juniperus sabina L, and related lignans against larvae of Pieris rapae L.Pest Manag Sci. 2004 Nov;60(11):1131-6.

Other Notes

Small volumes of Deoxypodophyllotoxin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Deoxypodophyllotoxin purchase

MBS5759837 is an inhibitor targeting Deoxypodophyllotoxin.