Ginsenoside F4 Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

767.01

<1mg/ml refers to the product slightly soluble or insoluble

C42H70O12

[H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)C[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C3C(C)(C)[C@H](O)CC[C@]3(C)[C@@]1([H])C[C@@H]2O)C(\C)=C\C\C=C(/C)C

181225-33-2

Bcl-2
MMP
IL Receptor

In this study, the inhibitory and apoptosis-inducing effect of Ginsenoside F4 (GF4) from steamed notoginseng was investigated by using human lymphocytoma Jurkat (JK) cell. Cell Counting Kit-8 method was then used to assess the anti-proliferative effect of GF4, and Western blotting was run to detect the expression level of two apoptosis-related proteins including Bax and the Bcl-2. The results suggested that GF4 can effectively inhibit the proliferation of the cells, and Bax expression increased gradually, but Bcl-2 expression reduced with the increase of GF4 concentration[1]

Apoptosis; BCL; Proteases/Proteasome; Immunology/Inflammation