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Morellic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759862

Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5uM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Morellic acid, Inhibitor
Full Product Name
Morellic acid
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
560.64
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C33H36O8
SMILES
CC(C)([C@H](C[C@H]1C=C23)[C@]33Oc(c(CC=C(C)C)c4OC(C)(C)C=Cc4c4O)c4C2=O)O[C@@]3(C/C=C(/C)\C(O)=O)C1=O
CAS Number
5304-71-2
Target & IC50
Others
In Vitro
An improved HPLC method was developed to simultaneously quantify 12 caged xanthones, including three pairs of epimers and four pairs of trans-cis isomers, i.e. forbesione, isoMorellic acid, Morellic acid, R-30-hydroxygambogic acid, S-30-hydroxygambogic acid, isogambogenic acid, gambogenic acid, gambogellic acid, R-isogambogic acid, S-isogambogic acid, R-gambogic acid and S-gambogic acid. This method was validated to be sensitive, precise and accurate with limits of detection of 0.03-0.08microg/mL, overall intra-day and inter-day variations less than 7.9% and overall recovery over 93.2%. The correlation coefficients (r(2)) of the calibration curves were higher than 0.995 for all analytes. The newly established method was successfully applied to reveal the difference in the chemical profiles and contents of these analytes in gamboges from different origins.

Product References and Citations for Morellic acid, inhibitor

Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin fromGarcinia hanburyi. Biomedical Chromatography, 2008, 22(6):637-644.

Other Notes

Small volumes of Morellic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Morellic acid purchase

MBS5759862 is an inhibitor targeting Morellic acid.
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