1-O-Acetyl britannilactone Inhibitor

Name: 1-O-Acetyl britannilactone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759893
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759893

1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

1-O-Acetyl britannilactone, Inhibitor

Full Product Name

1-O-Acetyl britannilactone

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

308.37

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C17H24O5

SMILES

CC1=C([C@@H]([C@H]2[C@@H](C1)OC(=O)C2=C)O)C(C)CCCOC(=O)C

CAS Number

681457-46-5

Target & IC50

p65
NF-kappaB
COX

In Vitro

The content of the compound ABL in flowers crude extract was tested with high performance liquid chromatography. The inhibitory effects of compound ABL against Sphaerotheca fuliginea,Pseudoperonospora cubensis,Botrytis cinerea,Alternaria solani and Phytophthora infestans were tested. The chemical structure of ABL reference substance was elucidated by using ultraviolet spectrometry(UV), infrared spectroscopy(IR), nuclear magnetic resonance(NMR). The purity of ABL reference substance was 99.5%,which satisfies the need of reference substances of traditional Chinese medicines. A method of high performance liquid chromatography was used for the determination of the content of ABL in crude extract from I.japonica flowers(it's 2.45%),then the content of ABL in I.japonica was calculated(it's about 0.25%)[1]

Product Categories/Family for 1-O-Acetyl britannilactone, inhibitor

NF-kappab; NF-kappaB; Immunology/Inflammation

Product References and Citations for 1-O-Acetyl britannilactone, inhibitor

Separation and analysis of 1-O-acetylbritannilactone from Inula japonica and determination of antifungal activityActa Phytophylacica Sinica, 2008, 35 (6) :551-6.
Separation and analysis of 1-O-acetylbritannilactone from Inula japonica and determination of antifungal activityActa Phytophylacica Sinica, 2008, 35 (6) :551-6.
1-o-acetylbritannilactone Inhibits Inflammatory Response by Suppressing NF-kappaB ActivationChinese Journal of Cell Biology, 2007, 29 (2) :267-71.

Other Notes

Small volumes of 1-O-Acetyl britannilactone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 1-O-Acetyl britannilactone purchase

MBS5759893 is an inhibitor targeting 1-O-Acetyl britannilactone.