16beta,17-Dihydroxy-ent-kaurane-19-oic acid Inhibitor

Name: 16beta,17-Dihydroxy-ent-kaurane-19-oic acid Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759943
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759943

16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 value of 0.8 microgram/mL. It also possesses the activities of decompression and blood viscosity… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

16beta,17-Dihydroxy-ent-kaurane-19-oic acid, Inhibitor

Full Product Name

16beta,17-Dihydroxy-ent-kaurane-19-oic acid

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

336.47

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C20H32O4

SMILES

C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@H](C3)[C@@](C4)(CO)O)(C)C(=O)O

CAS Number

74365-74-5

Target & IC50

HIV

In Vitro

Phytochemical analysis of the fruits of Annona squamosa yielded 12 known kaurane derivatives (1-11, 13) and two new kaurane diterpenoids, which have been named annosquamosin A (16 beta-hydroxy-17-acetoxy-ent-kauran-19-al) (12) and annosquamosin B (19-nor-ent-kaurane-4 alpha,16 beta,-17-triol) (14). The structures of the new compounds were established by spectral analyses and chemical evidence[1]

Product Categories/Family for 16beta,17-Dihydroxy-ent-kaurane-19-oic acid, inhibitor

Microbiology/Virology; HIV Protease

Product References and Citations for 16beta,17-Dihydroxy-ent-kaurane-19-oic acid, inhibitor

Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.J Nat Prod. 1996 Jun;59(6):635-7.
Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.J Nat Prod. 1996 Jun;59(6):635-7.
Diterpenes from Helianthus annuus and their cytotoxicity in vitro.Yao Xue Xue Bao. 2007 Feb;42(2):166-70.

Other Notes

Small volumes of 16beta,17-Dihydroxy-ent-kaurane-19-oic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 16beta,17-Dihydroxy-ent-kaurane-19-oic acid purchase

MBS5759943 is an inhibitor targeting 16beta,17-Dihydroxy-ent-kaurane-19-oic acid.