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3,8-Di-O-methylellagic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759990

3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
3,8-Di-O-methylellagic acid, Inhibitor
Full Product Name
3,8-Di-O-methylellagic acid
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
330.3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C16H10O8
SMILES
COc(c(O)cc(C(Oc1c2OC)=O)c3-c1c1cc2O)c3OC1=O
CAS Number
2239-88-5
Target & IC50
Antifection
NO Synthase
TNF-alpha
In Vitro
The methanolic extract from the barks of the medicinal plant Qualea parviflora (Vochysiaceae) was fractionated by column chromatography over silica gel followed by gel permeation over Sephadex LH-20 to give 3,3'-di-O-methylellagic acid-4-O-beta-D-glucopyranoside (1), 3-O-methylellagic acid-4'-O-alpha-L-rhamnopyranoside (2), 3,3',4-tri-O-methylellagic acid-4'-O-beta-D-glucopyranoside (3), and 3,3'-di-O-methylellagic acid (3,8-Di-O-methylellagic acid,4), together with triterpenes and saponins. We also performed comparative analyses among this species and Q. grandiflora and Q. multiflora using high-pressure liquid chromatography[1]

Product References and Citations for 3,8-Di-O-methylellagic acid, inhibitor

Identification of ellagic acid derivatives in methanolic extracts from Qualea species.Z Naturforsch C. 2008 Nov-Dec;63(11-12):794-800.
Identification of ellagic acid derivatives in methanolic extracts from Qualea species.Z Naturforsch C. 2008 Nov-Dec;63(11-12):794-800.
Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.J Agric Food Chem. 2008 Dec 24;56(24):11668-74.
Chemical Constituents with DPPH Radical Scavenging, Elastase Inhnbition and Tyrosinase Inhibition Activities from Cleyera japonica ThunbKorean Society for Biotechnology and Bioengineering, 2011,4, 272-272.

Other Notes

Small volumes of 3,8-Di-O-methylellagic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5759990 is an inhibitor targeting 3,8-Di-O-methylellagic acid.
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