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3-Epiursolic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759997

3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5uM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
3-Epiursolic acid, Inhibitor
Full Product Name
3-Epiursolic acid
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
456.7
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C30H48O3
SMILES
[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@@H](O)C2(C)C
CAS Number
989-30-0
Target & IC50
Cathepsins L (catL): ic50
Immunology & Inflammation related
In Vitro
All three extracts were found to exhibit antiinflammatory activity with the chloroform extract being the most active. Chemical investigations of petroleum ether and chloroform extracts led to the isolation of beta-sitosterol, ursolic acid, oleanolic acid, 3-Epiursolic acid, 3-epioleanolic acid, and minor triterpenoids of derivatives of ursolic acid and oleanolic acids. Chromatographic purification of the methanol extract yielded two iridoid glucosides, verbenalin and hastatoside, a phenylpropanoid glycoside, verbascoside and beta-sitosterol-D-glucoside.

Product References and Citations for 3-Epiursolic acid, inhibitor

Antiinflammatory activity and chemical composition of extracts of Verbena officinalis.Phytother Res. 2000 Sep;14(6):463-5.

Other Notes

Small volumes of 3-Epiursolic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 3-Epiursolic acid purchase

MBS5759997 is an inhibitor targeting 3-Epiursolic acid.
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