4',7-Dihydroxyflavone Inhibitor

Name: 4',7-Dihydroxyflavone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760021
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760021

4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

4',7-Dihydroxyflavone, Inhibitor

Full Product Name

4',7-Dihydroxyflavone

Product Synonym Names

7,4'-Dihydroxyflavone

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

254.1

Solubility

DMSO: 250mg/mL (983.32mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C15H10O4

SMILES

Oc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1

CAS Number

2196-14-7

Target & IC50

COX
NOD1

In Vitro

Root exudate from 3-day-old alfalfa seedlings was purified and then assayed for biological activity with a nodABC-lacZ fusion in R. meliloti. Indentities of major nod inducers were established by spectroscopic analyses (ultraviolet/visible, proton nuclear magnetic resonance, and mass spectroscopy) and comparison with authentic standards. Major nod inducers, which were identified as 4',7-Dihydroxyflavone, 4'-7-dihydroxyflavanone, and 4,4'-dihydroxy-2'-methoxychalcone, were released from seedling roots at 54, 22, and 20 picomole.plant(-1).day(-1), respectively. Luteolin was not found in these root exudates.

Product Categories/Family for 4',7-Dihydroxyflavone, inhibitor

Immunology/Inflammation; COX; NF-kappab

Product References and Citations for 4',7-Dihydroxyflavone, inhibitor

A Chalcone and Two Related Flavonoids Released from Alfalfa Roots Induce nod Genes of Rhizobium meliloti.Plant Physiol., 1989, 91(3):842-7.

Other Notes

Small volumes of 4',7-Dihydroxyflavone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 4',7-Dihydroxyflavone purchase

MBS5760021 is an inhibitor targeting 4',7-Dihydroxyflavone.