7-O-Methylrosmanol Inhibitor

Name: 7-O-Methylrosmanol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760081
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760081

7-O-Methylrosmanol can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

7-O-Methylrosmanol, Inhibitor

Full Product Name

7-O-Methylrosmanol

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

360.45

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C21H28O5

SMILES

[H][C@@]12[C@@H]3OC(=O)[C@@]1(CCCC2(C)C)c1c(O)c(O)c(cc1[C@@H]3OC)C(C)C

CAS Number

113085-62-4

Target & IC50

cAMP

In Vitro

In order to find new effective HIV protease inhibitors, two diterpenes (carnosic acid and carnosol) were isolated from rosemary (Rosmarinus officinalis L.), and rosmanol and semisynthetic derivatives (7-O-Methylrosmanol, 7-O-ethylrosmanol, and 11,12-O,O-dimethylcarnosol) were prepared. The inhibitory activity of all six compounds against HIV-1 protease was tested. The carnosic acid showed the strongest inhibitory effect (IC90 = 0.08 micrograms/ml). The same compound was also assayed against HIV-1 virus replication (IC90 = 0.32 micrograms/ml).

Product Categories/Family for 7-O-Methylrosmanol, inhibitor

GPCR/G Protein; cAMP

Product References and Citations for 7-O-Methylrosmanol, inhibitor

Inhibitory effect of carnosic acid on HIV-1 protease in cell-free assays.J Nat Prod. 1993 Aug;56(8):1426-30.

Other Notes

Small volumes of 7-O-Methylrosmanol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 7-O-Methylrosmanol purchase

MBS5760081 is an inhibitor targeting 7-O-Methylrosmanol.