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(+)-Afzelechin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760105

(+)-Afzelechin has a neuroprotective effect on the glutamate-induced neurotoxicity in HT22 cells, it has ABTS cation radical scavenging effects with IC50 values of 23.7microM More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
(+)-Afzelechin, Inhibitor
Full Product Name
(+)-Afzelechin
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
274.3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H14O5
SMILES
O[C@@H](C1)[C@@H](c(cc2)ccc2O)Oc2c1c(O)cc(O)c2
CAS Number
2545-00-8
Target & IC50
Others
In Vitro
Antioxidant activity (AOA) assay-guided chemical analysis, using a rat pancreas homogenate model, of aerial parts from Eysenhardtia subcoriacea, led to isolation of the new compound subcoriacin (3-(2'-hydroxy-4',5'-methylendioxyphenyl)-6-(3''-hydroxymethyl-4''-hydroxybut-2''-enyl)-7-hydroxycoumarin) together with the known substances: (+)-catechin, (-)-epicatechin, (+)-Afzelechin, eriodictyol, (+)-catechin 3-O-beta-D-galactopyranoside and quercetin 3-O-beta-D-galactopyranoside as bioactive constituents. The structure of the compound was determined from 1D and 2DnMR spectroscopic analyses. Additional known constituents were characterized[1]

Product References and Citations for (+)-Afzelechin, inhibitor

Antioxidant aryl-prenylcoumarin, flavan-3-ols and flavonoids from Eysenhardtia subcoriacea.Phytochemistry. 2008 Jan;69(2):451-6.
Antioxidant aryl-prenylcoumarin, flavan-3-ols and flavonoids from Eysenhardtia subcoriacea.Phytochemistry. 2008 Jan;69(2):451-6.
Neuroprotective and free radical scavenging activities of phenolic compounds from Hovenia dulcis. Arch Pharm Res. 2005 Jul;28(7):804-9.

Other Notes

Small volumes of (+)-Afzelechin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (+)-Afzelechin purchase

MBS5760105 is an inhibitor targeting (+)-Afzelechin.
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