Alismol Inhibitor

Name: Alismol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760111
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760111

Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Alismol, Inhibitor

Full Product Name

Alismol

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

220.4

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C15H24O

SMILES

CC(C)C(CCC([C@H]1CC2)=C)=C[C@H]1[C@]2(C)O

CAS Number

87827-55-2

Target & IC50

Calcium Channel
Potassium Channel
PI3K

In Vitro

Alismol (10(-6) to 10(-4) M) inhibited the contraction of isolated rabbit ear artery by electrical stimulation of the perivascular nerves. The inhibition was concentration-dependent; at a concentration of 10(-4) M, the inhibition was 90% (n = 8). treatment with 10(-4) M Alismol inhibited the increase in 3H-noradrenaline (3H-NAd) release induced by electrical stimulation by 63 +/- 6%. Alismol at 10(-4) M did not affect the neuronal uptake of 3H-NAd in the artery. Alismol at 10(-4) M slightly inhibited contractions induced by exogenously administered NAd[1]

Product Categories/Family for Alismol, inhibitor

Membrane transporter/Ion channel; Calcium Channel; PI3K/Akt/mTOR signaling

Product References and Citations for Alismol, inhibitor

Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.
Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.
Effects of alismol isolated from Alismatis Rhizoma on calcium-induced contraction in the rabbit thoracic aorta.Life Sci. 1987 Oct 12;41(15):1845-52.
Effect of alismol isolated from Alismatis Rhizoma on working heart perfusion in rat. Phytother. Res., 1989, 3(2):72-4.

Other Notes

Small volumes of Alismol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Alismol purchase

MBS5760111 is an inhibitor targeting Alismol.