Betulinic acid methyl ester Inhibitor

Name: Betulinic acid methyl ester Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760185
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760185

Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Betulinic acid methyl ester, Inhibitor

Full Product Name

Betulinic acid methyl ester

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

470.7

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C31H50O3

SMILES

CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C(=O)OC

CAS Number

2259-06-5

Target & IC50

Antifection

In Vitro

These substances showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro, with IC(50) values of 9.89, 10.01, 5.99, 51.58, and 45.79microM, respectively. Mice infected with Plasmodium berghei and treated with betulinic acid acetate had a dose-dependent reduction of parasitemia[1]

Product Categories/Family for Betulinic acid methyl ester, inhibitor

Microbiology/Virology; Antifection

Product References and Citations for Betulinic acid methyl ester, inhibitor

Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice.Parasitol Res. 2009 Jul;105(1):275-9.
Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice.Parasitol Res. 2009 Jul;105(1):275-9.
Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.J Nat Prod. 2002 May;65(5):645-8.

Other Notes

Small volumes of Betulinic acid methyl ester, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Betulinic acid methyl ester purchase

MBS5760185 is an inhibitor targeting Betulinic acid methyl ester.