Bisabolangelone Inhibitor

Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-kappaB signaling.

HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.Fitoterapia. 2011 Apr;82(3):434-40.
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.Fitoterapia. 2011 Apr;82(3):434-40.
Hypopigmenting activity of bisabolangelone isolated from Angelica koreana Maxim. in alpha+/--melanocyte stimulating hormone-activated B16 or melan-a cells.Planta Med. 2011 Feb;77(3):248-51.
Kim H S, Lee Y J, Lee H K, et al. Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-kappaB signaling[J]. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association, 2013, 59.
Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62.

Small volumes of Bisabolangelone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5760188 is an inhibitor targeting Bisabolangelone.