Cajanin Inhibitor

Name: Cajanin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760201
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760201

Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cajanin, Inhibitor

Full Product Name

Cajanin

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

300.3

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C16H12O6

SMILES

COc(cc1O)cc(OC=C2c(ccc(O)c3)c3O)c1C2=O

CAS Number

32884-36-9

Target & IC50

MEK
ERK
Akt

In Vitro

Glucose uptake assay-guided fractionations on the methanol extract of Sophorae Flos led to the isolation of the flavonoids rutin (1), narcissin (2), quercetin (3), tamarixetin (4), and kaempferol (5) and the isoflavonoids Cajanin (6), genistein (7), orobol (8), and pratensein (9). Among them, 1, 4, 5, 6, 8, and 9 significantly improved basal glucose uptake in HepG2 cells. Their improving effects were concentration dependent. Compounds 4, 5, 6, and 9 exhibited effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug. However, 2, 3, and 7 did not show any improving effects. Stimulating glucose uptake into peripheral cells may be responsible for reducing the level of blood glucose in the circulation.

Product Categories/Family for Cajanin, inhibitor

MAPK; MEK; Cytoskeletal Signaling

Product References and Citations for Cajanin, inhibitor

Flavonoids and isoflavonoids from Sophorae Flos improve glucose uptake in vitro.Planta Med. 2010 Jan;76(1):79-81.

Other Notes

Small volumes of Cajanin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cajanin purchase

MBS5760201 is an inhibitor targeting Cajanin.