Canthin-6-one Inhibitor

Name: Canthin-6-one Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760205
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760205

Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflammatory activity by interfering with the transcription factors NF-kappaB and AP-1 at transcriptional… More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Canthin-6-one, Inhibitor

Full Product Name

Canthin-6-one

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

220.2

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C14H8N2O

SMILES

O=C(C=C1)n2c3c1nccc3c1c2cccc1

CAS Number

479-43-6

Target & IC50

Caspase
Antifection
NF-kappaB

In Vitro

A new alkaloid, 4,5-dimethoxy-10-hydroxyCanthin-6-one (1), was isolated from the stem of Picrasma quassioides Bennet (Simaroubaceae) together with four known Canthin-6-one alkaloids, 8-hydroxyCanthin-6-one (2), 4,5-dimethoxyCanthin-6-one (3), 5-hydroxy-4-methoxyCanthin-6-one (4), and 3-methylcanthin-5,6-dione (5). Their structures were elucidated on the basis of spectroscopic data. The cytotoxic activity of the Canthin-6-one alkaloids was evaluated using human nasopharyngeal carcinoma (CNE2) and human liver cancer (Bel-7402) cell lines.

Product Categories/Family for Canthin-6-one, inhibitor

Apoptosis; Caspase; Microbiology&virology; NF-kappab

Product References and Citations for Canthin-6-one, inhibitor

Canthin-6-one alkaloids from Picrasma quassioides and their cytotoxic activity.J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1009-12.

Other Notes

Small volumes of Canthin-6-one, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Canthin-6-one purchase

MBS5760205 is an inhibitor targeting Canthin-6-one.