Chamaechromone Inhibitor

Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by alpha+/--naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2.

Metabolites characterization of chamaechromone in vivo and in vitro by using ultra-performance liquid chromatography/Xevo G2 quadrupole time-of-flight tandem mass spectrometry.J Ethnopharmacol. 2014;151(1):242-52.
Metabolites characterization of chamaechromone in vivo and in vitro by using ultra-performance liquid chromatography/Xevo G2 quadrupole time-of-flight tandem mass spectrometry.J Ethnopharmacol. 2014;151(1):242-52.
Metabolism of chamaechromone in vitro with human liver microsomes and recombinant human drug-metabolizing enzymes.Planta Med. 2014 Apr;80(6):493-7.

Small volumes of Chamaechromone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5760221 is an inhibitor targeting Chamaechromone.