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Cinobufotenine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760238

Cinobufotenine is a potent stimulant of parasympathetic ganglia and its effect are competitively antagonized by hexamethonium. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cinobufotenine, Inhibitor
Full Product Name
Cinobufotenine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
219.3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C13H19N2O
SMILES
C[N+](C)(C)CCC1=CNC2=C1C=C(C=C2)O
CAS Number
60657-23-0
Target & IC50
Others
In Vitro
1 Coryneine is 2.7 times as active as Cinobufotenine on the frog rectus but on the guinea-pig ileum Cinobufotenine is 1.5 times as active as coryneine. Cinobufotenine is a potent stimulant of parasympathetic ganglia and its effect are competitively antagonized by hexamethonium. 2 The effects of pH on activity relative to a standard whose ionisation is constant (Me4+N or the trimethylammonium analogue of tryptamine) are consistent with the phenate form being weaker than the phenolic form but the changes are smaller than with coryneine because Cinobufotenine is a weaker acid.

Product References and Citations for Cinobufotenine, inhibitor

A comparison of cinobufotenine (the quaternary derivative of 5-HT) and some related compounds with coryneine (the quaternary derivative of dopamine) on the frog rectus, guinea-pig ileum and rat fundus strip preparations. Br J Pharmacol. 1980 Aug;69(4):597-600.

Other Notes

Small volumes of Cinobufotenine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cinobufotenine purchase

MBS5760238 is an inhibitor targeting Cinobufotenine.
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