Clemastanin B Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

684.7

<1mg/ml refers to the product slightly soluble or insoluble

C32H44O16

COc(cc(C[C@@H]1[C@H](CO)[C@@H](c(cc2)cc(OC)c2O[C@@H]([C@@H]([C@H]2O)O)O[C@H](CO)[C@H]2O)OC1)cc1)c1O[C@@H]([C@@H]([C@H]1O)O)O[C@H](CO)[C@H]1O

112747-98-5

Influenza virus
Immunology & Inflammation related

The experiment consisted of four parts: therapeutic action, prophylaxsis action, inhibition of virus attachment, and direct virucidal action. Cytopathic effect (CPE) and 3-(4,5-Dimethylthiazol-2-yI)-2,5-diphenyltetrazolium (MTT) were used to assess antiviral activity. CB, epigoitrin, PEP and PEP ALK OA fractions from Banlangen (Radix Isatidis) extract significantly increased the viability of MDCK cells pre-infected with the virus compared with the virus control group in all the dilutions (P <0.01). Pretreated with either pure compounds or chemical fractions of Banlangen (Radix Isatidis) extract in all the dilutions significantly improved the viability of MDCK cells (P <0.01). The inhibition of virus absorption to the host cells by CB, epigoitrin and PEP was in a dose dependent manner.

Microbiology/Virology; Influenza Virus; Immunology/Inflammation