Combretol Inhibitor

Name: Combretol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760256
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760256

Combretol has leishmanicidal activity, it showed moderate activity (growth inhibition 87.3 and 73.0 %, respectively, at 50uM) against a multidrug-resistant L. tropica line. Combretol also shows weakly active cytotoxic activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Combretol, Inhibitor

Full Product Name

Combretol

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

388.4

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C20H20O8

SMILES

COc(cc1O)cc(OC(c(cc2OC)cc(OC)c2OC)=C2OC)c1C2=O

CAS Number

5084-19-5

Target & IC50

Antifection

In Vitro

A new bicyclic diterpene with a labdane skeleton, 7-oxo-labd-8-en-15-ol (1), along with two known diterpenes and ten flavonoids were isolated from the leaves of Aeonium lindleyi (Crassulaceae). Their structures were elucidated on the basis of spectroscopic data, including 1D and 2DnMR experiments, and comparison with spectroscopic data reported in the literature[1]

Product Categories/Family for Combretol, inhibitor

Microbiology/Virology; Antifection

Product References and Citations for Combretol, inhibitor

Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi.Planta Med. 2011 Jan;77(1):77-80.
Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi.Planta Med. 2011 Jan;77(1):77-80.
Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest.J Nat Prod. 2006 Feb;69(2):287-9.

Other Notes

Small volumes of Combretol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Combretol purchase

MBS5760256 is an inhibitor targeting Combretol.