Continentalic acid Inhibitor

Name: Continentalic acid Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760258
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760258

Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Continentalic acid, Inhibitor

Full Product Name

Continentalic acid

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

302.5

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C20H30O2

SMILES

C[C@@](CCC1)([C@H](CC2)[C@]1(C)C(O)=O)[C@H](CC1)C2=C[C@@]1(C)C=C

CAS Number

19889-23-7

Target & IC50

COX
PGE
NOS

In Vitro

Percentage of growth inhibition was evaluated by sulphorhodamine B assay. Purified Continentalic acid showed moderate cytotoxicity against all the cell lines used. In contrast, the extract exhibited significant concentration dependant cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines[1]

Product Categories/Family for Continentalic acid, inhibitor

Immunology/Inflammation; COX; GPCR/G Protein

Product References and Citations for Continentalic acid, inhibitor

In vitro Cytotoxicity of Methanol Extract from Aerial Parts of Aralia cachemirica and Purified Continentalic Acid. Indian J Pharm Sci. 2015 Nov-Dec;77(6):792-5.
In vitro Cytotoxicity of Methanol Extract from Aerial Parts of Aralia cachemirica and Purified Continentalic Acid. Indian J Pharm Sci. 2015 Nov-Dec;77(6):792-5.
Anti-inflammatory activity of the constituents of the roots of Aralia continentalis. Arch Pharm Res. 2009 Sep;32(9):1237-43.
Continentalic acid from Aralia continentalis shows activity against methicillin-resistant Staphylococcus aureus.Phytother Res. 2006 Jun;20(6):511-4.

Other Notes

Small volumes of Continentalic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Continentalic acid purchase

MBS5760258 is an inhibitor targeting Continentalic acid.