Eriodictyol-7-O-glucoside Inhibitor

Name: Eriodictyol-7-O-glucoside Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760352
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760352

Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Eriodictyol-7-O-glucoside, Inhibitor

Full Product Name

Eriodictyol-7-O-glucoside

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

450.39

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C21H22O11

SMILES

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1Oc1cc(O[C@@H](CC2=O)c(cc3)cc(O)c3O)c2c(O)c1

CAS Number

38965-51-4

Target & IC50

Nrf2

In Vitro

Eriodictyol-7-O-glucoside as a novel nuclear factor E2-related factor 2 (Nrf2) activator using a high-throughput cellular screening method. This compound activated Nrf2 signaling pathway and was able to stabilize Nrf2 by delaying Nrf2 degradation, resulting in accumulation of Nrf2 protein and activation of the Nrf2-dependent protective response. Recent studies have suggested that activation of Nrf2 pathway would confer protection against cisplatin-induced toxicity. The protective role of Eriodictyol-7-O-glucoside in cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC. Co-treatment of HRMC cells with Eriodictyol-7-O-glucoside significantly improved cell survival under cisplatin exposure[1]

Product Categories/Family for Eriodictyol-7-O-glucoside, inhibitor

Immunology/Inflammation; Nrf2

Product References and Citations for Eriodictyol-7-O-glucoside, inhibitor

Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity.Food Chem Toxicol. 2012 Jun;50(6):1927-32.
Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity.Food Chem Toxicol. 2012 Jun;50(6):1927-32.
Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins. Biochimie. 2010 Sep;92(9):1115-22.

Other Notes

Small volumes of Eriodictyol-7-O-glucoside, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Eriodictyol-7-O-glucoside purchase

MBS5760352 is an inhibitor targeting Eriodictyol-7-O-glucoside.