Eurycomalactone Inhibitor

Name: Eurycomalactone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760368
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760368

Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-kappaB inhibitor(IC50 of 0.5uM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFalpha-induced degradation of IkappaBalpha… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Eurycomalactone, Inhibitor

Full Product Name

Eurycomalactone

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

348.4

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C19H24O6

SMILES

C[C@@H]([C@H]([C@@H]([C@@H]([C@@]1(C)C(C[C@H]2C(C)=CC3=O)=O)[C@@]2(C)[C@@H]3O)O)O2)[C@@H]1C2=O

CAS Number

23062-24-0

Target & IC50

NF-kappaB: ic50 1uM
Antifection

Product Categories/Family for Eurycomalactone, inhibitor

NF-kappab; NF-kappaB; Microbiology&virology

Product References and Citations for Eurycomalactone, inhibitor

Cytotoxic activity of quassinoids from Eurycoma longifolia.Nat Prod Commun. 2010 Jul;5(7):1009-12.
Cytotoxic activity of quassinoids from Eurycoma longifolia.Nat Prod Commun. 2010 Jul;5(7):1009-12.
Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance.Fitoterapia. 2010 Oct;81(7):669-79.
Dukaew N, Konishi T, Chairatvit K, et al. Enhancement of Radiosensitivity by Eurycomalactone in Human NSCLC Cells through G2/M Cell Cycle Arrest and Delayed DNA Double-strand Break Repair[J]. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 2019.
Antiplasmodial studies of Eurycoma longifolia Jack using the lactate dehydrogenase assay of Plasmodium falciparum.J Ethnopharmacol. 2004 Jun;92(2-3):223-7.

Other Notes

Small volumes of Eurycomalactone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Eurycomalactone purchase

MBS5760368 is an inhibitor targeting Eurycomalactone.