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Isotetrandrine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760533

Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-kappaB, which may involve the inhibition of tissue… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Isotetrandrine, Inhibitor
Full Product Name
Isotetrandrine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
622.8
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C38H42N2O6
SMILES
CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
CAS Number
477-57-6
Target & IC50
IL Receptor
NF-kappaB
MAPK

Product References and Citations for Isotetrandrine, inhibitor

Isotetrandrine protects against lipopolysaccharide-induced acute lung injury by suppression of mitogen-activated protein kinase and nuclear factor-kappa B.J Surg Res. 2014 Apr;187(2):596-604.

Other Notes

Small volumes of Isotetrandrine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Isotetrandrine purchase

MBS5760533 is an inhibitor targeting Isotetrandrine.
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