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Jatropholone B Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760537

Jatropholone B shows antiproliferative activity against cancer cell lines. It also has gastroprotective activity in preventing the gastric lesions in mice. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Jatropholone B, Inhibitor
Full Product Name
Jatropholone B
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
296.41
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C20H24O2
SMILES
C[C@H](Cc(c1c(c([C@H]2C(C)(C)[C@H]2CC2)c3C)C2=C)c3O)C1=O
CAS Number
71386-38-4
Target & IC50
Others
In Vitro
The cells used comprised normal lung fibroblasts (MRC-5), gastric adenocarcinoma (AGS), leukemia (HL-60), lung cancer (SK-MES-1), and bladder carcinoma (J82). Jatropholone A (1) was inactive against all the tumor cell lines; however, its acetylation rendered a compound with antiproliferative activity. The epimeric Jatropholone B (8) was active against all the cancer cell lines, and its derivatives presented different effects on the selected cell lines.

Product References and Citations for Jatropholone B, inhibitor

Antiproliferative activity of the diterpenes jatrophone and jatropholone and their derivatives.Planta Med. 2009 Nov;75(14):1520-2.

Other Notes

Small volumes of Jatropholone B, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Jatropholone B purchase

MBS5760537 is an inhibitor targeting Jatropholone B.
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