Licoflavonol Inhibitor

Name: Licoflavonol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760583
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760583

Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Licoflavonol, Inhibitor

Full Product Name

Licoflavonol

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

354.35

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C20H18O6

SMILES

CC(C)=CCc(c(O)c(c(OC(c(cc1)ccc1O)=C1O)c2)C1=O)c2O

CAS Number

60197-60-6

Target & IC50

Antifection

In Vitro

In this study, twenty prenylated flavonoids (1-20) were screened for their anti-T3SS activity, revealing that several analogs exhibited strong inhibitory effects on the secretion of Salmonella pathogenicity island 1 (SPI-1)-associated effector proteins without affecting the growth of bacteria and the secretion of the flagellar protein FliC. Among the flavonoids 1-20, Licoflavonol (20) exhibited a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC.

Product Categories/Family for Licoflavonol, inhibitor

Microbiology/Virology; Antifection

Product References and Citations for Licoflavonol, inhibitor

Licoflavonol is an inhibitor of the type three secretion system of Salmonella enterica serovar Typhimurium. Biochem Biophys Res Commun. 2016 Sep 2;477(4):998-1004.

Other Notes

Small volumes of Licoflavonol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Licoflavonol purchase

MBS5760583 is an inhibitor targeting Licoflavonol.