Lucidenic acid A Inhibitor

Lucidenic acid-A and -F are modulators of JNK and p38, respectively, they enhance LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK MAPKs activation.

Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFalpha+/- induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK. Biochem Biophys Res Commun. 2011 Apr 29;408(1):18-24.
Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFalpha+/- induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK. Biochem Biophys Res Commun. 2011 Apr 29;408(1):18-24.
Two new triterpenoids, lucidenic acid N (1) and methyl lucidenate F (2), together with four known compounds, lucidenic acid A, lucidenolactone, lucidenic acid C, and ganoderic acid E, were isolated from the dried fruiting bodies of Ganoderma lucidum. TheiJ. Nat.Prod., 2001, 64(64):1121-2.

Small volumes of Lucidenic acid A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5760598 is an inhibitor targeting Lucidenic acid A.