Lucidenic acid C Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

476.6

<1mg/ml refers to the product slightly soluble or insoluble

C27H40O7

C[C@H](CCC(O)=O)[C@@H](CC1=O)[C@@](C)([C@@H]2O)[C@]1(C)C([C@H](C[C@@H](C1(C)C)[C@]3(C)CC[C@@H]1O)O)=C3C2=O

95311-96-9

MMP

Triterpenoid components in the ethanol extract of G. lucidum (YK-02) were separated by means of a semi-preparative RP HPLC. Four major peaks were separated and crystallized from triterpenoids fraction, and were identified as lucidenic acid A, lucidenic acid B, Lucidenic acid C, and lucidenic acid N according to their spectroscopic values of (1)HnMR and MS. treatment of the lucidenic acids (50microM) in the presence of 200nM phorbol 12-myristate 13-acetate (PMA) after 24 hours of incubation all resulted in significant inhibitory effects on PMA-inducedmMP-9 activity and invasion of HepG(2)cells.

Proteases/Proteasome; MMP