Mulberroside F Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

566.5

<1mg/ml refers to the product slightly soluble or insoluble

C26H30O14

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1Oc1cc(oc(-c2cc(O[C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)cc(O)c2)c2)c2cc1

193483-95-3

Tyrosinase

The current study was carried out to investigate the in vitro effects of an 85% methanol extract of dried Morus alba leaves on melanin biosynthesis, which is closely related to hyperpigmentation. These extracts inhibited the tyrosinase activity that converts dopa to dopachrome in the biosynthetic process of melanin. Mulberroside F (moracin M-6, 3'-di-O-beta-D-glucopyranoside), which was obtained after the bioactivity-guided fractionation of the extracts, showed inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells. This compound also exhibited superoxide scavenging activity that is involved in the protection against auto-oxidation. But its activity was low and was weaker than of kojic acid.

Proteases/Proteasome; Tyrosinase