Mussaenoside Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

390.4

<1mg/ml refers to the product slightly soluble or insoluble

C17H26O10

C[C@](CC[C@H]12)([C@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@H](CO)[C@H]2O)OC=C1C(OC)=O)O

64421-27-8

TNF-alpha
IL Receptor
NF-kappaB

The ethanolic extract of the aerial parts of Castilleja tenuiflora was separated by silica gel column chromatography. The fractions were evaluated using the induced edema acetate 12-O-tetradecanoylphorbol (TPA) anti-inflammatory activity model. The most active fraction was subjected to medium-pressure liquid chromatography (MPLC) with UV detection at 206 and 240nM. The following iridoids were isolated: geniposidic acid, aucubin, bartioside, 8-epi-loganin, Mussaenoside, and the phenylpropanoid verbascoside. The most active iridoid was geniposidic acid, which was more active than the control (indomethacin), and the least active iridoid was Mussaenoside. 8-epi-Loganin, and Mussaenoside have not been previously reported to be anti-inflammatory compounds[1]

Apoptosis; TNF; Immunology/Inflammation; NF-kappab