p-Hydroxyphenethyl trans-ferulate Inhibitor

Name: p-Hydroxyphenethyl trans-ferulate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760746
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760746

P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6microM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

p-Hydroxyphenethyl trans-ferulate, Inhibitor

Full Product Name

p-Hydroxyphenethyl trans-ferulate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

314.3

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C18H18O5

SMILES

COc(cc(/C=C/C(OCCc(cc1)ccc1O)=O)cc1)c1O

CAS Number

84873-15-4

Target & IC50

5-HT

In Vitro

Crude nonpolar solvent extracts were prepared from freeze-dried green onion by sequential refluxing with hexane and then ethyl acetate, followed by liquid-liquid extraction. Active fractions were subjected to the Hepa 1c1c7 bioassay-guided steps of flash chromatography, thin layer chromatography (TLC), and high-pressure preparative liquid chromatography (HPLC) to afford pure isolates capable of inducing QR. Multiple fractions were active in inducing QR. Five pure compounds were isolated from active fractions and identified using spectroscopic methods; these were p-Hydroxyphenethyl trans-ferulate (1), 5,6-dimethyl-2-pyridinecarboxylic acid (2), ferulic acid (3), 1-(6-hydroxy-[3]pyridyl)-propan-1-one (4), and N-trans-feruloyl 3-O-methyldopamine (5).

Product Categories/Family for p-Hydroxyphenethyl trans-ferulate, inhibitor

GPCR/G Protein; 5-HT Receptor

Product References and Citations for p-Hydroxyphenethyl trans-ferulate, inhibitor

Isolation and identification of phase II enzyme-inducing agents from nonpolar extracts of green onion (Allium spp.).J Agric Food Chem. 2006 Nov 1;54(22):8417-24.

Other Notes

Small volumes of p-Hydroxyphenethyl trans-ferulate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for p-Hydroxyphenethyl trans-ferulate purchase

MBS5760746 is an inhibitor targeting p-Hydroxyphenethyl trans-ferulate.