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Pachypodol Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760748

Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pachypodol, Inhibitor
Full Product Name
Pachypodol
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
344.3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C18H16O7
SMILES
COc(cc1O)cc(OC(c(cc2)cc(OC)c2O)=C2OC)c1C2=O
CAS Number
33708-72-4
Target & IC50
Antifection
In Vitro
Pachypodol (5,4'-dihydroxy-3,7,3'-trimethoxyflavone) has been isolated from the leaves of C. floribunda by repeated column chromatography on silica gel, and the structure confirmed by spectroscopic means. While the general toxicity of Pachypodol was determined by the brine shrimp lethality assay, the cytotoxic potential of this flavonoid has been evaluated by the Promega's CellTiter 96 Non-Radioactive Cell Proliferation Assay using the CaCo-2 colon cancer cell line (IC(50) = 185.6microM). A summary of the biological activities of Pachypodol reported to date is also presented[1]

Product References and Citations for Pachypodol, inhibitor

Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro.Phytother Res. 2008 Dec;22(12):1684-7.
Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro.Phytother Res. 2008 Dec;22(12):1684-7.
Pachypodol from Croton ciliatoglanduliferus Ort. as water-splitting enzyme inhibitor on thylakoids.J Agric Food Chem. 2006 Feb 22;54(4):1217-21.
Antifungal Flavonoids from Ballota glandulosissima.Pharm. Biol., 2003, 41(7):483-6.
Anti-emetic principles of Pogostemon cablin (Blanco) Benth.Phytomedicine. 1999 May;6(2):89-93.

Other Notes

Small volumes of Pachypodol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pachypodol purchase

MBS5760748 is an inhibitor targeting Pachypodol.
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