Pinocembrin chalcone Inhibitor

Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic activation of heterocyclic amines. Pinocembrin chalcone shows antimicrobial activity against the antibiotic susceptible NG strain WHO V ; it also displays activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL.

Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae.Sex Transm Dis. 2011 Feb;38(2):82-8
Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae.Sex Transm Dis. 2011 Feb;38(2):82-8
Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors. Bioorg Med Chem. 2007 Mar 15;15(6):2396-402.
Structural analysis of a novel antimutagenic compound, 4-Hydroxypanduratin A, and the antimutagenic activity of flavonoids in a Thai spice, fingerroot (Boesenbergia pandurata Schult.) against mutagenic heterocyclic amines.J Agric Food Chem. 2001 Jun;49(6):3046-50.

Small volumes of Pinocembrin chalcone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5760792 is an inhibitor targeting Pinocembrin chalcone.