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(-)-Praeruptorin B Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760812

MBS5760812 is an inhibitor targeting (-)-Praeruptorin B. (-)-Praeruptorin B is a natural product from Peucedanum praeruptorum Dunn. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
(-)-Praeruptorin B, Inhibitor
Full Product Name
(-)-Praeruptorin B
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
426.45
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C24H26O7
SMILES
C\C=C(\C)C(=O)O[C@H]1[C@@H](OC(=O)C(\C)=C/C)C(C)(C)Oc2ccc3ccc(=O)oc3c12
CAS Number
4970-26-7
Target & IC50
Others
In Vitro
In current study, a rapid and reliable online solid phase extraction-chiral high performance liquid chromatography-tandem mass spectrometry (online SPE-chiral LC-MS/MS) method was developed for the simultaneously enantiospecific quantitation of (+)-trans-khellactone (dTK), (+/-)-cis-khellactone (d/lCK), (+/-)-praeruptorin A (d/lPA), (+)-praeruptorin B/(-)-Praeruptorin B (d/lPB) and (+)-praeruptorin E (dPE), the main active angular-type pyranocoumarins (APs) in Peucedani Radix (Chinese name: Qian-hu) or the major metabolites of those APs, in rat plasma.

Product References and Citations for (-)-Praeruptorin B, inhibitor

Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS.J Pharm Biomed Anal. 2014 Jan;88:269-77.

Other Notes

Small volumes of (-)-Praeruptorin B, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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