Pseudohypericin Inhibitor

Name: Pseudohypericin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760828
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760828

Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pseudohypericin, Inhibitor

Full Product Name

Pseudohypericin

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

520.44

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C30H16O9

SMILES

CC1=CC(=O)C2=C(C3=C(C=C(C4=C3C5=C2C1=C6C(=CC(=O)C7=C(C8=C(C=C(C4=C8C5=C67)O)O)O)CO)O)O)O

CAS Number

55954-61-5

Target & IC50

PGE
NO Synthase

In Vitro

Since hypericin has been proposed as a photosensitizer for photodynamic cancer therapy, the photocytotoxicity of its congener Pseudohypericin has been investigated. The presence of foetal calf serum (FCS) or albumin extensively inhibits the photocytotoxic effect of Pseudohypericin against A431 tumour cells, and is associated with a large decrease in cellular uptake of the compound. These results suggest that Pseudohypericin, in contrast to hypericin, interacts strongly with constituents of FCS, lowering its interaction with cells[1]

Product Categories/Family for Pseudohypericin, inhibitor

GPCR/G Protein; Prostaglandin Receptor; Immunology/Inflammation

Product References and Citations for Pseudohypericin, inhibitor

Photocytotoxic effect of pseudohypericin versus hypericin.J.Photoch.Photobiol. B, 1998, 45(2-3):87-94.
Photocytotoxic effect of pseudohypericin versus hypericin.J.Photoch.Photobiol. B, 1998, 45(2-3):87-94.
Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin.P. Natl. Acad. Sci., 1989, 86(15):5963-7.
Download citationShare Request full-text Pseudohypericin in Hypericum perforatum inhibited LPS-stimulated PGE2 and NO in mouse macrophages by potentiating SOCS3 expressionCancer Prev. Res., 2010, 3(12 Supplement).

Other Notes

Small volumes of Pseudohypericin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pseudohypericin purchase

MBS5760828 is an inhibitor targeting Pseudohypericin.