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Robustine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760871

MBS5760871 is an inhibitor targeting Robustine. Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Robustine, Inhibitor
Full Product Name
Robustine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
215.2
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C12H9NO3
SMILES
COc(c1ccc2)c(cco3)c3nc1c2O
CAS Number
2255-50-7
Target & IC50
Immunology & Inflammation related
PDE
In Vitro
Eight new compounds, including four new neolignans, (7' S,8' S)-bilagrewin (1), (7' S,8' S)-5-demethoxybilagrewin (2), (7' S,8' S)-5- O-demethyl-4'- O-methylbilagrewin (3), and (7' S,8' S)-nocomtal (4), a new coumarinolignan, (7' S,8' S)-4'- O-methylcleomiscosin D (5), two new lignan derivatives, (+)-9'- O-(Z)-feruloyl-5,5'-dimethoxylariciresinol (6) and (+)-9'- O-(E)-feruloyl-5,5'-dimethoxylariciresinol (7), and a new chromene, (E)-3-(2,2-dimethyl-2 H-chromen-6-yl)prop-2-enal (8), have been isolated from the stem wood of Zanthoxylum avicennae, together with 18 known compounds (9- 26). The structures of these new compounds were determined through spectroscopic and MS analyses[1]

Product References and Citations for Robustine, inhibitor

Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae.J Nat Prod. 2008 Feb;71(2):212-7.
Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae.J Nat Prod. 2008 Feb;71(2):212-7.
Inhibitory effects of furoquinoline alkaloids from Melicope confusa and Dictamnus albus against human phosphodiesterase 5 (hPDE5A) in vitro. Arch Pharm Res. 2005 Jun;28(6):675-9.

Other Notes

Small volumes of Robustine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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