Seneciphylline N-oxide Inhibitor

Seneciphylline N-oxide and senecionine N-oxide are probably tumorigenic due to their potential conversion into seneciphylline and senecionine via metabolic reduction in the body.

Site of synthesis, metabolism and translocation of senecionine N-oxide in cultured roots of Senecio erucifoliusPlant Cell, Tissue and Organ Culture, 1989,18(1):19-31.
Site of synthesis, metabolism and translocation of senecionine N-oxide in cultured roots of Senecio erucifoliusPlant Cell, Tissue and Organ Culture, 1989,18(1):19-31.
Selective sequestration and metabolism of plant derived pyrrolizidine alkaloids by chrysomelid leaf beetlesPhytochemistry,1997,45(3):489-497.
Experience influences gustatory responsiveness to pyrrolizidine alkaloids in the polyphagous caterpillar, Estigmene acreaJournal of Comparative Physiology A,2003,189(11):833-841.

Small volumes of Seneciphylline N-oxide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5760913 is an inhibitor targeting Seneciphylline N-oxide.