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Tartrazine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760966

Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect, may be harmful to health and its prolonged use could trigger carcinogenesis. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tartrazine, Inhibitor
Full Product Name
Tartrazine
Product Synonym Names
Acid Yellow 23; FD&C Yellow No. 5
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
534.36
Solubility
DMSO: 10mg/mL (18.71mM)
Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C16H9N4Na3O9S2
SMILES
C1=CC(=CC=C1N=NC2C(=NN(C2=O)C3=CC=C(C=C3)S(=O)(=O)[O-])C(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+]
CAS Number
1934-21-0
Target & IC50
Others
In Vitro
We assessed the cytotoxicity of Tartrazine by 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide test and the response of DNA repair through comet assay (alkaline version). We used different concentrations of the dye, ranging from 0.25-64.0mM. The results demonstrated that Tartrazine has no cytotoxic effects. However, this dye had a significant genotoxic effect at all concentrations tested. Although most of the damage was amenable to repair, some damage remained higher than positive control after 24 hours of repair[1]

Product References and Citations for Tartrazine, inhibitor

Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow. Anticancer Res. 2015 Mar;35(3):1465-74.
Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow. Anticancer Res. 2015 Mar;35(3):1465-74.
Assessment of the breakdown products of solar/UV induced photolytic degradation of food dye tartrazine.Food Chem Toxicol. 2014 Jun;68:307-15.

Other Notes

Small volumes of Tartrazine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tartrazine purchase

MBS5760966 is an inhibitor targeting Tartrazine.
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