Tectoquinone Inhibitor

Solid. Powder

99.95%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

222.20

<1mg/ml refers to the product slightly soluble or insoluble

C15H10O2

CC1=CC2=C(C=C1)C(=O)C1=CC=CC=C1C2=O

84-54-8

Others

Mosquito larvicidal activities of methanolic extracts from different plant parts of red heartwood-type Cryptomeria japonica D. Don against the fourth-instar larvae of Aedes aegypti and Aedes albopictus were examined. Results of mosquito larvicidal tests demonstrated that the n-hexane fraction of C. japonica sapwood methanolic extract had an excellent inhibitory effect against the larvae of A. aegypti and A. albopictus and its LC50 values were 2.4 and 3.3microg/ml, respectively, in 24hours. Following the bioactivity-guided fractionation procedure, the active constituent isolated from C. japonica sapwood was characterized as Tectoquinone by spectroscopic analyses. The LC50 values of Tectoquinone against A. aegypti and A. albopictus in 24h were 3.3 and 5.4microg/ml, respectively. In addition, comparisons of mosquito larvicidal activity of anthraquinone congeners demonstrated that anthraquinone skeleton with a methyl group at C-2 position, such as Tectoquinone, exhibited the strongest mosquito larvicidal activity.