Tokinolide B Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

380.48

<1mg/ml refers to the product slightly soluble or insoluble

C24H28O4

CCC[C@H]([C@H](CC[C@]12/C(/O3)=C/CCC)C=C1C3=O)[C@@]2(C1=C2C=CCC1)OC2=O

112966-16-2

Others

The chemical constituents of the organic extracts from the rhizomes of Ligusticum porteri were isolated, characterised and identified as Z-ligustilide, Z-butylidenephthalide, diligustilide, Tokinolide B, riligustilide, senkyunolides F and I, ferulic acid, among other known compounds. The preparation of 4,5-dehydroTokinolide B from Tokinolide B is reported, and its structure confirmed by X-ray analysis. The sedative and spasmolytic activities of some of these natural products and derivatives were evaluated by applying them to in vivo and in vitro models.