Eleutheroside B1 Inhibitor

Name: Eleutheroside B1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5761034
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5761034

Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Eleutheroside B1, Inhibitor

Full Product Name

Eleutheroside B1

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

384.33

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C17H20O10

SMILES

COc(cc(C=CC(O1)=O)c1c1OC)c1O[C@H]([C@@H]([C@H]1O)O)O[C@H](CO)[C@H]1O

CAS Number

16845-16-2

Target & IC50

Influenza virus

Cell Research

A549 cells were seeded in 6-well plates at 37 degree C in an atmosphere of 5% CO2, then infected with influenza virus (strain A/PR/8/34; 0.1 MOI) and subsequently treated with eleutheroside B1 at a diluted concentration. At 24 hour post-infection, the cells were collected for mRNA expression analysis of the host genes (MAN2A2, POLR2A) and the viral genes [polymerase acid (PA), polymerase basic (PB) 1 and 2 and hemagglutinin (HA)] by RT-qPCR.

Product Categories/Family for Eleutheroside B1, inhibitor

Microbiology/Virology; Influenza Virus

Product References and Citations for Eleutheroside B1, inhibitor

Wen, Yan, Chunge, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.[J]. International Journal of Molecular Medicine, 2018.

Other Notes

Small volumes of Eleutheroside B1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Eleutheroside B1 purchase

MBS5761034 is an inhibitor targeting Eleutheroside B1.