Cyclocurcumin Inhibitor

Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment,of rheumatoid arthritis as predicted by the MM-PBSA method. It may have a therapeutic potential as a novel antivasoconstrictive natural product. Cyclocurcumin offers higher neuronal protection than curcumin, they both reduced the level of ROS caused by MPP+ treatment.

Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP+) induced neurotoxicity in differentiated PC12 cells. Sci Rep. 2017 Dec 5;7(1):16977.
Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment,of rheumatoid arthritis as predicted by the MM-PBSA method. Int J Mol Med. 2017 May;39(5):1164-1172.
Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric). J Nat Prod. 2017 Jan 27;80(1):196-200.
Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res. 2013 Sep;57(9):1529-42.

Small volumes of Cyclocurcumin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5762148 is an inhibitor targeting Cyclocurcumin.