Isofuranodiene Inhibitor

Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment,of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells; it can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. Isofuranodiene at concentrations of 25 and 12.5 lM alone, or in combination with 50nM nerve growth factor (NGF), shows a marked stimulation of neuritogenesis,which appears to be a promising neurotrophic and neuroprotective agent.

Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines. ScientificWorldJournal. 2014;2014:264829.
Isofuranodiene: A neuritogenic compound isolated from wild celery (Smyrnium olusatrum L., Apiaceae). Food Chem. 2016 Feb 1;192:782-7.

Small volumes of Isofuranodiene, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5762580 is an inhibitor targeting Isofuranodiene.