(+)-Lyoniresinol Inhibitor

Lyoniresinol has antioxidant effect, it shows robust anti-melanogenic activity, decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulated MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression.

Antimicrobial property of (+)-lyoniresinol-3alpha-O-beta-D-glucopyranoside isolated from the root bark of Lycium chinense Miller against human pathogenic microorganisms. Arch Pharm Res. 2005 Sep;28(9):1031-6.
Lyoniresinol inhibits melanogenic activity through the induction of microphthalmia-associated transcription factor and extracellular receptor kinase activation. Mol Cell Biochem. 2013 Jan;373(1-2):211-6.
Changes in Lyoniresinol Content and Antioxidative Activity of Pickled Ume during the Seasoning Process. West African J. Med., 1994, 13(1):495-8.

Small volumes of (+)-Lyoniresinol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5762710 is an inhibitor targeting (+)-Lyoniresinol.