Sambutoxin Inhibitor

Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers, it can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, and, finally, death when rats were fed diets supplemented with 0.05 and 0.1% sambutoxin. Sambutoxin has in vitro cytotoxicity against various human and murine tumor cells and values of sambutoxin ranged from 46.2 to 1,425.6ng/ml. It inhibits rabbit platelet aggregation, which may be party due to the decrease of ATP release.

Sambutoxin-producing isolates of fusarium species and occurrence of sambutoxin in rotten potato tubers. Appl Environ Microbiol. 1995 Oct;61(10):3750-1.
In vitro Cytotoxicity of Sambutoxin. Agric. Chem. Biotechnol.,1988,41(4):273-4.

Small volumes of Sambutoxin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5763063 is an inhibitor targeting Sambutoxin.