Vestitol Inhibitor

Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10mg/kg, and shows MICs ranging from 25-50 to 50-100ug/mL and MBCs ranging from 25-50 to 50-100ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemical barrier against the intrusion of the parasite.

Anti-inflammatory and antimicrobial evaluation of neovestitol and vestitol isolated from Brazilian red propoli. J Agric Food Chem. 2013 May 15;61(19):4546-50.
Vestitol as a chemical barrier against intrusion of parasitic plant Striga hermonthica into Lotus japonicus roots. Biosci Biotechnol Biochem. 2010;74(8):1662-7.
Vestitol: A phytoalexin with insect feeding-deterrent activity. J. Chem. Ecol.,1978,4(5):571 -9.

Small volumes of Vestitol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5763292 is an inhibitor targeting Vestitol.