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Dolastatin 10 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5763465

Dolastatin 10 is a potent antimitotic polypeptide isolated from a marine animal and is developed as a potential antitumor agent. Dolastatin 10 is found to have activity to inhibit tubulin polymerization with IC50 value of 1.2uM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dolastatin 10, Inhibitor
Full Product Name
Dolastatin 10
Product Synonym Names
DLS 10; NSC 376128
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
785.09
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C42H68N6O6S
CAS Number
110417-88-4

Product References and Citations for Dolastatin 10, inhibitor

Pitot HC, et al. Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res. 1999 Mar;5(3):525-31.
Pettit GR, et al. Antineoplastic agents. 592. Highly effective cancer cell growth inhibitory structural modifications ofdolastatin 10. J Nat Prod. 2011 May 27;74(5):962-8.
Brentuximab vedotin. Drugs R D. 2011;11(1):85-95.

Other Notes

Small volumes of Dolastatin 10, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dolastatin 10 purchase

MBS5763465 is an inhibitor targeting Dolastatin 10.
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